BackgroundSpermidine/Spermine N1-Acetyltransferase 1 (SAT1) is a protein coding gene that belongs to the acetyltransferase family. Considered a rate-limiting enzyme in the catabolic pathway of polyamine metabolism, this protein catalyzes the acetylation of spermidine and spermine. It also participates in the regulation of the intracellular concentration of polyamines and their movement out of cells. Mutations in this gene are linked to keratosis follicularis spinulosa decalvans (KFSD). Alternatively spliced transcripts have been identified for SAT1.
DescriptionSAT1 Polyclonal Antibody . Unconjugated. Raised in: Rabbit.
FormulationBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SpecificityHuman
IsotypeIgG
Uniprot IDP21673
PurificationAffinity Purification
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 1-171 of human SAT1 (NP_002961.1).
StorageShipped at 4°C. Upon receipt, store at -20°C. Avoid freeze / thaw cycles
Alternative NamesSAT, DC21, KFSD, SSAT, KFSDX, SSAT-1
ApplicationWB; Recommended dilution: WB: 1:500-1:2000