BackgroundThis gene encodes a nuclear protein which is involved in cell-cycle regulation. The encoded protein is a ubiquitin-ligase capable of ubiquinating PCNP (PEST-containing nuclear protein), and together they may play a role in tumorigenesis. The encoded protein contains an NIRF_N domain, a PHD finger, a set- and ring-associated (SRA) domain, and a RING finger domain and several of these domains have been shown to be essential for the regulation of cell proliferation. This protein may also have a role in intranuclear degradation of polyglutamine aggregates. Alternative splicing results in multiple transcript variants some of which are non-protein coding.
DescriptionUHRF2 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationLiquid. PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SpecificityHuman, Mouse, Rat
IsotypeIgG
Uniprot IDQ7TMI3
PurificationAffinity Purified
ImmunogenRecombinant Protein of Mouse Uhrf2
StorageShipped at 4°C. Store at -20°C. Avoid multiple freeze/thaw cycles.
Alternative NamesNIRF, URF2, RNF107, RP11-472F14.2
ApplicationWB; Recommended dilution: WB 1:500 - 1:2000