SIRT3 Polyclonal Antibody

Background
This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Two alternatively spliced transcript variants that encode different proteins have been described for this gene.

Description
SIRT3 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.

Formulation
Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.

Specificity
Human, Mouse, Rat

Isotype
IgG

Uniprot ID
Q9NTG7

Purification
Affinity Purified

Immunogen
A synthetic peptide corresponding to a sequence within amino acids 299-399 of human SIRT3 (NP_036371.1).

Storage
Shipped at 4°C. Store at -20°C. Avoid freeze / thaw cycles.

Alternative Names
SSIRT3; SIR2L3; sirtuin 3, T3

Application
WB, IHC, IF; Recommended Dilutions: WB 1:500 - 1:1000, IHC-P 1:20 - 1:50, IF/ICC 1:50 - 1:200