Phospho-EEF2K-S366 Polyclonal Antibody

Background
This gene encodes a highly conserved protein kinase in the calmodulin-mediated signaling pathway that links activation of cell surface receptors to cell division. This kinase is involved in the regulation of protein synthesis. It phosphorylates eukaryotic elongation factor 2 (EEF2) and thus inhibits the EEF2 function. The activity of this kinase is increased in many cancers and may be a valid target for anti-cancer treatment.

Description
Phospho-EEF2K-S366 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.

Formulation
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Specificity
Human, Mouse, Rat

Isotype
IgG

Uniprot ID
O00418

Purification
Affinity Purification

Immunogen
A synthetic phosphorylated peptide around S366 of human EEF2K (NP_037434.1).

Storage
Shipped at 4°C. Upon receipt, store at -20°C. Avoid freeze / thaw cycles

Alternative Names
EEF2K; HSU93850; eEF-2K; eukaryotic elongation factor 2 kinase

Application
WB; Recommended dilution: WB 1:500 - 1:2000