BackgroundPromotes the exchange of Ras-bound GDP by GTP. Probably by promoting Ras activation, regulates phosphorylation of MAP kinase MAPK3 in response to EGF. Catalytic component of a trimeric complex that participates in transduction of signals from Ras to Rac by promoting the Rac-specific guanine nucleotide exchange factor (GEF) activity (By similarity).
DescriptionSOS1 Recombinant Monoclonal Antibody [2B2]. Unconjugated. Raised in: HEK293F Cell.
FormulationBuffer: Rabbit IgG in phosphate buffered saline, pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
SpecificityHuman
IsotypeRabbit IgG
Uniprot IDQ07889
PurificationAffinity Chromatography
ImmunogenA synthesized peptide derived from Human SOS1
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesSon of sevenless homolog 1 (SOS-1), SOS1
ApplicationELISA, FC; Recommended dilution: FC:1:50-1:200