BackgroundThe Spike glycoprotein, encoded by the S gene in SARS-CoV-2, is a vital component responsible for virus binding and entry into host cells. It undergoes various processing steps, resulting in the formation of S1 and S2 subunits. Notably, the presence of a furin polybasic cleavage site sets SARS-CoV-2 apart from its predecessor, SARS-CoV. The S1 subunit contains the receptor binding domain (RBD), which facilitates entry into sensitive cells via the ACE2 receptor. The S2 domain is responsible for membrane fusion. DescriptionSARS-CoV-2 Spike RBD Nanobody, HRP conjugated [A1]. HRP. Raised in: HEK293F Cell.
FormulationBuffer: 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.
SpecificityHuman Novel Coronavirus (SARS-CoV-2/ 2019-nCoV)
IsotypeVHH fusion with human IgG1 Fc
Uniprot IDP0DTC2
PurificationAffinity Chromatography
ImmunogenRecombinant Human Novel Coronavirus Spike glycoprotein(S) (319-541aa)
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesS; 2; Spike glycoprotein; S glycoprotein; E2; Peplomer protein
ApplicationELISA; Recommended dilution: ELISA:1:1000-1:500000