S Recombinant Monoclonal Antibody, HRP conjugated [H6]

Background
The Spike glycoprotein, encoded by the S gene in SARS-CoV-2, is a vital component responsible for virus binding and entry into host cells. It undergoes various processing steps, resulting in the formation of S1 and S2 subunits. Notably, the presence of a furin polybasic cleavage site sets SARS-CoV-2 apart from its predecessor, SARS-CoV. The S1 subunit contains the receptor binding domain (RBD), which facilitates entry into sensitive cells via the ACE2 receptor. The S2 domain is responsible for membrane fusion. 

Description
S Recombinant Monoclonal Antibody, HRP conjugated [H6]. HRP. Raised in: HEK293F Cell.

Formulation
Buffer: 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.

Specificity
Human Novel Coronavirus (SARS-CoV-2/ 2019-nCoV)

Isotype
Mouse scFv fusion with human IgG1 Fc

Uniprot ID
P0DTC2

Purification
Affinity Chromatography

Immunogen
Recombinant Human Novel Coronavirus Spike glycoprotein (S) (16-685aa)

Storage
Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Alternative Names
S, S1, S1-RBD, Spike glycoprotein

Application
ELISA; Recommended dilution: ELISA:1:10000-1:50000