The EpiQuik Global Histone Acetylation Assay Kits (H3 and H4) Has Been Released Published 03/17/2006 |
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Epigentek Inc has released the new kits for measuring global histone H3 and H4 acetylation. Acetylation of histones including histone H3 and H4 has been involved in the regulation of chromatin structure and the recruitment of transcription factors to gene promoters. An imbalance in the equilibrium of histone acetylation has been associated with tumorigenesis and cancer progression. The quantification of global histone H3/H4 acetylation in cells could provide extremely useful information for analyzing this disease and evaluating effects of HDAC/HAT inhibitors. These kits use a unique procedure to quantify global histone acetylation. The assay can be completed within 5 hours in a high throughput format and without radioactivity and chromatography. | |||
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