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Signal Transduction Antibodies

Signal Transduction Antibodies

Signal transduction, or cell signaling, is the process by which various signals are transmitted throughout the cell in a cascading series of extracellular and intracellular molecular events involving lipids, proteins, and ions. Often it involves a signal from a secreted growth factor, hormone or other extracellular signaling molecule with binding to receptors at the cell surface, including receptor tyrosine kinases and G-protein coupled receptors, which then transduce the signal intracellularly. A wide range of antibodies are involved in signal transduction, such as cell surface receptor and kinase antibodies, intracellular kinase and adaptor protein antibodies, phosphatase antibodies, and secreted growth factor antibodies. Signaling pathways and their fluid dynamic processes can be studied by researchers aiming to learn more about their far-reaching morphological effects and especially their influence on the regulation of gene expression. Signal transduction antibodies can also offer insight into various pathways and their role in the development of diseases, for example, Alzheimer’s, lupus, cancer and rheumatoid arthritis.

What makes buying antibodies from EpiGentek different?

At EpiGentek, we supply a collection of over 20,000 individual high-quality antibodies for our customers to ensure that our research customers find exactly what they need for their studies. In addition, we offer a variety of other benefits to help our customers in terms of affordability, convenience, and reliability. See why working with EpiGentek for your antibodies is the right choice:

  • No Shipping & Handling Costs: we’ve waived all shipping and handling fees on our antibodies and antibody panel packs (trial sizes not applicable).
  • 100% Application Guarantee: your purchased antibodies are covered for 6-months past the date of purchase.
  • Multiple Conjugates: we carry biotin, FITC and HRP conjugates for nearly all targets.
  • Trial Sizes Available: 10 & 20 µg options available on over 5,000 antibodies in our catalog.

Cell Surface Receptor & Kinase Antibodies
Cell surface receptors transduce signals from the exterior of the cell to the interior by binding to secreted or extracellular factors, including hormones, growth factors, neurotransmitters, or other molecules. Cell surface receptors are generally classified by their tertiary structure or their membrane topology. Cell surface receptors include enzyme-linked receptors, G-protein coupled receptors and ion channel-linked receptors. Transduction of the intracellular signal can be mediated by protein-protein interactions by effector proteins, or by enzymatic activity as in the case of the enzyme-linked receptors. The enzyme-linked receptors usually possess enzymatic activity themselves, or associate with kinases or other enzymatic proteins intracellularly.

Intracellular Kinase & Adaptor Protein Antibodies
After binding of a ligand or secreted factor to its cell surface receptor, an intracellular signal is transduced, which is mediated by enzymatic activity of the receptor itself, as in the case of receptor tyrosine kinases, and by effector or adaptor proteins bound to specific intracellular domains of the receptor.

Phosphatase Antibodies
Phosphorylation is a major post-translational modification to proteins and controls cell signaling and induction of cell proliferation, differentiation, cell death and other biological processes. Phosphatases reverse phosphorylation by removing the phosphate group added by kinases mostly to serine, threonine or tyrosine residues in a protein. Thus phosphatases have a critical role in regulating cell signaling, as generally reversal of the phosphorylation indicates a switching off of the signal. Uncontrolled or constitutive signaling by cell surface receptors may lead to increased proliferation, among other outcomes, and could lead to the pathogenesis of cancer and other diseases. Therefore, after phosphorylation and protein activation by kinases, the signal must return to the resting or inactivated state through dephosphorylation catalyzed by phosphatases.

Secreted Growth Factor Antibodies
Growth factors, peptide hormones, neurotransmitters and other secreted molecules initiate diverse signals involved in controlling cellular growth and proliferation, tissue development and differentiation, cellular metabolism and other biological processes. They initiate signals by binding to a receptor on the cell surface, which then undergoes a conformational change leading to an intracellular signaling cascade.

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AKT2 Polyclonal Antibody
AKT2 Polyclonal Antibody

Application: ELISA, IF, IHC, WB
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human, Rat
Trial Size Available: Yes
A56166-02020 µg $99.00 Add to Cart
A56166-05050 µg $256.00 Add to Cart
A56166-100100 µg $359.00 Add to Cart
Antibodies
AKT2 Polyclonal Antibody, Biotin Conjugated
AKT2 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A56169-05050 µg $256.00 Add to Cart
A56169-100100 µg $359.00 Add to Cart
Antibodies
AKT2 Polyclonal Antibody, FITC Conjugated
AKT2 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A56168-05050 µg $256.00 Add to Cart
A56168-100100 µg $359.00 Add to Cart
Antibodies
AKT2 Polyclonal Antibody, HRP Conjugated
AKT2 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A56167-05050 µg $256.00 Add to Cart
A56167-100100 µg $359.00 Add to Cart
Antibodies
AMH Polyclonal Antibody
AMH Polyclonal Antibody

Application: ELISA, IF, IHC, WB
Areas of Research: Cell Development & Differentiation, Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A56138-02020 µg $99.00 Add to Cart
A56138-05050 µg $256.00 Add to Cart
A56138-100100 µg $359.00 Add to Cart
Antibodies
Amh Polyclonal Antibody
Amh Polyclonal Antibody

Application: ELISA, IHC, WB
Areas of Research: Cell Development & Differentiation, Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human, Mouse
Trial Size Available: Yes
A54922-02020 µg $99.00 Add to Cart
A54922-05050 µg $256.00 Add to Cart
A54922-100100 µg $359.00 Add to Cart
Antibodies
AMH Polyclonal Antibody, Biotin Conjugated
AMH Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation, Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A56141-05050 µg $256.00 Add to Cart
A56141-100100 µg $359.00 Add to Cart
Antibodies
Amh Polyclonal Antibody, Biotin Conjugated
Amh Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation, Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Mouse
A54919-05050 µg $256.00 Add to Cart
A54919-100100 µg $359.00 Add to Cart
Antibodies
Amh Polyclonal Antibody, FITC Conjugated
Amh Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation, Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Mouse
A54920-05050 µg $256.00 Add to Cart
A54920-100100 µg $359.00 Add to Cart
Antibodies
AMH Polyclonal Antibody, FITC Conjugated
AMH Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation, Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A56140-05050 µg $256.00 Add to Cart
A56140-100100 µg $359.00 Add to Cart
Antibodies
AMH Polyclonal Antibody, HRP Conjugated
AMH Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation, Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A56139-05050 µg $256.00 Add to Cart
A56139-100100 µg $359.00 Add to Cart
Antibodies
Amh Polyclonal Antibody, HRP Conjugated
Amh Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Cell Development & Differentiation, Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Mouse
A54921-05050 µg $256.00 Add to Cart
A54921-100100 µg $359.00 Add to Cart
Antibodies
Amyloid Beta A4 Protein A Polyclonal Antibody
Amyloid Beta A4 Protein A Polyclonal Antibody

Application: ELISA, WB
Areas of Research: Immunology & Inflammation, Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A57755-02020 µg $99.00 Add to Cart
A57755-05050 µg $256.00 Add to Cart
A57755-100100 µg $359.00 Add to Cart
Antibodies
Amyloid Beta A4 Protein A Polyclonal Antibody
Amyloid Beta A4 Protein A Polyclonal Antibody

Application: ELISA, IF, IHC, WB
Areas of Research: Immunology & Inflammation, Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human, Mouse
Trial Size Available: Yes
A57756-02020 µg $99.00 Add to Cart
A57756-05050 µg $256.00 Add to Cart
A57756-100100 µg $359.00 Add to Cart
Antibodies
ANG1 Polyclonal Antibody
ANG1 Polyclonal Antibody

Application: ELISA
Areas of Research: Cell Growth, Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Bovine
Trial Size Available: Yes
A57654-02020 µg $99.00 Add to Cart
A57654-05050 µg $256.00 Add to Cart
A57654-100100 µg $359.00 Add to Cart
Antibodies
ANG1 Polyclonal Antibody, Biotin Conjugated
ANG1 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Growth, Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Bovine
A57657-05050 µg $256.00 Add to Cart
A57657-100100 µg $359.00 Add to Cart
Antibodies
ANG1 Polyclonal Antibody, FITC Conjugated
ANG1 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Cell Growth, Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Bovine
A57656-05050 µg $256.00 Add to Cart
A57656-100100 µg $359.00 Add to Cart
Antibodies
ANG1 Polyclonal Antibody, HRP Conjugated
ANG1 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Cell Growth, Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Bovine
A57655-05050 µg $256.00 Add to Cart
A57655-100100 µg $359.00 Add to Cart
Antibodies
ANGPT1 Polyclonal Antibody
ANGPT1 Polyclonal Antibody

Application: ELISA, IHC, WB
Areas of Research: Cell Growth, Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A57770-02020 µg $99.00 Add to Cart
A57770-05050 µg $256.00 Add to Cart
A57770-100100 µg $359.00 Add to Cart
Antibodies
ANGPT1 Polyclonal Antibody, Biotin Conjugated
ANGPT1 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Cell Growth, Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A57772-05050 µg $256.00 Add to Cart
A57772-100100 µg $359.00 Add to Cart
Antibodies
Result Pages:  1  2  3  4  5 ...  [Next >>]  Displaying 1 to 20 (of 2525 products)
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