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DNA Methylation Antibody Panel Pack

Phosphatase Antibodies

Phosphorylation is a major post-translational modification to proteins and controls cell signaling and induction of cell proliferation, differentiation, cell death and other biological processes. Phosphatases reverse phosphorylation by removing the phosphate group added by kinases mostly to serine, threonine or tyrosine residues in a protein. Thus phosphatases have a critical role in regulating cell signaling, as generally reversal of the phosphorylation indicates a switching off of the signal. Uncontrolled or constitutive signaling by cell surface receptors may lead to increased proliferation, among other outcomes, and could lead to the pathogenesis of cancer and other diseases. Therefore, after phosphorylation and protein activation by kinases, the signal must return to the resting or inactivated state through dephosphorylation catalyzed by phosphatases.

Two important phosphatases include the serine/threonine protein phosphatase 2A (PP2A) and phosphatase and tensin homolog (PTEN). PP2A is a key phosphatase as it catalyzes dephosphorylation of many proteins, but also dephosphorylates the main protein kinases responsible for activation of major signaling pathways, including AKT, ERK MAP kinase and Protein kinase C (PKC) family members. PTEN dephosphorylates proteins, as well as the phospholipid phosphatidylinositol (3,4,5)-trisphosphate (PIP3), which induces inhibition of signaling by AKT, a critical pathway involved in cellular growth and proliferation. PTEN is a tumor suppressor frequently mutated and involved in the pathogenesis and progression of several cancers.
Result Pages: [<< Prev]   1  2  3  4  5 ...  [Next >>]  Displaying 21 to 40 (of 182 products)
ILKAP Polyclonal Antibody
ILKAP Polyclonal Antibody

Application: ELISA, WB
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human, Mouse, Rat
Trial Size Available: Yes
A54596-02020 µgView
A54596-05050 µgView
A54596-100100 µgView
Antibodies
ILKAP Polyclonal Antibody, Biotin Conjugated
ILKAP Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A54593-05050 µgView
A54593-100100 µgView
Antibodies
ILKAP Polyclonal Antibody, FITC Conjugated
ILKAP Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A54594-05050 µgView
A54594-100100 µgView
Antibodies
ILKAP Polyclonal Antibody, HRP Conjugated
ILKAP Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A54595-05050 µgView
A54595-100100 µgView
Antibodies
INPP1 Polyclonal Antibody
INPP1 Polyclonal Antibody

Application: ELISA, IHC
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A59482-02020 µgView
A59482-05050 µgView
A59482-100100 µgView
Antibodies
INPP1 Polyclonal Antibody, Biotin Conjugated
INPP1 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A59483-05050 µgView
A59483-100100 µgView
Antibodies
INPP1 Polyclonal Antibody, FITC Conjugated
INPP1 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A59484-05050 µgView
A59484-100100 µgView
Antibodies
INPP1 Polyclonal Antibody, HRP Conjugated
INPP1 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A59485-05050 µgView
A59485-100100 µgView
Antibodies
INPP5A Polyclonal Antibody
INPP5A Polyclonal Antibody

Application: ELISA, IF, IHC
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A55251-02020 µgView
A55251-05050 µgView
A55251-100100 µgView
Antibodies
INPP5A Polyclonal Antibody, Biotin Conjugated
INPP5A Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A55254-05050 µgView
A55254-100100 µgView
Antibodies
INPP5A Polyclonal Antibody, FITC Conjugated
INPP5A Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A55253-05050 µgView
A55253-100100 µgView
Antibodies
INPP5A Polyclonal Antibody, HRP Conjugated
INPP5A Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A55252-05050 µgView
A55252-100100 µgView
Antibodies
INPP5B Polyclonal Antibody
INPP5B Polyclonal Antibody

Application: ELISA, IF, IHC
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A69555-02020 µgView
A69555-05050 µgView
A69555-100100 µgView
Antibodies
INPP5B Polyclonal Antibody, Biotin Conjugated
INPP5B Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A69558-05050 µgView
A69558-100100 µgView
Antibodies
INPP5B Polyclonal Antibody, FITC Conjugated
INPP5B Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A69557-05050 µgView
A69557-100100 µgView
Antibodies
INPP5B Polyclonal Antibody, HRP Conjugated
INPP5B Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A69556-05050 µgView
A69556-100100 µgView
Antibodies
MTMR11 Polyclonal Antibody
MTMR11 Polyclonal Antibody

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A62990-02020 µgView
A62990-05050 µgView
A62990-100100 µgView
Antibodies
MTMR11 Polyclonal Antibody, Biotin Conjugated
MTMR11 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A62993-05050 µgView
A62993-100100 µgView
Antibodies
MTMR11 Polyclonal Antibody, FITC Conjugated
MTMR11 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A62992-05050 µgView
A62992-100100 µgView
Antibodies
MTMR11 Polyclonal Antibody, HRP Conjugated
MTMR11 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Signal Transduction
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
A62991-05050 µgView
A62991-100100 µgView
Antibodies
Result Pages: [<< Prev]   1  2  3  4  5 ...  [Next >>]  Displaying 21 to 40 (of 182 products)
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