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KDM8 Polyclonal Antibody

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Immunohistochemistry of paraffin-embedded human testis tissue using KDM8 Polyclonal Antibody at dilution of 1:100
Application: ELISA, IHC
Areas of Research: Histone Methylation & Demethylation
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
100% Guarantee: 6 months
Catalog No.SizePriceQty
A59530-02020 µgView
A59530-05050 µgView
A59530-100100 µgView
Product Overview

Background
Histone demethylase required for G2/M phase cell cycle progression. Specifically demethylates dimethylated 'Lys-36' (H3K36me2) of histone H3, an epigenetic repressive mark, thereby acting as a transcription activator. Regulates expression of CCNA1 (cyclin-A1), leading to regulate cancer cell proliferation.

Description
KDM8 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.

Formulation
Liquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.

Specificity
Human

Isotype
IgG

Uniprot ID
Q8N371

Purification
>95%, Protein G purified

Immunogen
Recombinant Human Lysine-specific demethylase 8 protein (151-380AA)

Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.

Alternative Names
Lysine-specific demethylase 8 (EC:1.14.11.27), KDM8, JMJD5, JmjC domain-containing protein 5, Jumonji domain-containing protein 5

Application
ELISA, IHC; Recommended dilution: IHC:1:20-1:200

User Guide & MSDS

[User Guide]*
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