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ING3 Polyclonal Antibody

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Western blot analysis of extracts of various cell lines, using ING3 Polyclonal Antibody.
Immunofluorescence analysis of A549 cell using ING3 Polyclonal Antibody. Blue: DAPI for nuclear staining.
Application: IF, WB
Areas of Research: Histone Acetylation & Deacetylation
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Affinity Purified
Reactivity: Human, Mouse, Rat
100% Guarantee: 6 months
Catalog No.SizePriceQty
A-2729-05050 µlView
A-2729-100100 µlView
Product Overview

Background
The protein encoded by this gene is similar to ING1, a tumor suppressor protein that can interact with TP53, inhibit cell growth, and induce apoptosis. This protein contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This gene can activate p53 trans-activated promoters, including promoters of p21/waf1 and bax. Overexpression of this gene has been shown to inhibit cell growth and induce apoptosis. Allelic loss and reduced expression of this gene were detected in head and neck cancers. Two alternatively spliced transcript variants encoding different isoforms have been observed.

Description
ING3 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.

Specificity
Human, Mouse, Rat

Isotype
IgG

Uniprot ID
Q9NXR8

Purification
Affinity Purified

Immunogen
Recombinant Protein of Human ING3

Storage
Shipped at 4°C. Store at -20°C. Avoid multiple freeze/thaw cycles.

Alternative Names
Eaf4, ING2, MEAF4, p47ING3

Application
WB, IF

User Guide & MSDS

[User Guide]*
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DNA Methylation Antibody Panel Pack
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