Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a replication-dependent histone that is a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21.3
Histone H3R8 Dimethyl Symmetric (H3R8me2s) Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Human, Mouse, Rat, Broad Range
Synthetic Peptide of Human Symmetric DiMethyl-Histone H3-R8
Shipped at 4°C. Store at -20°C. Avoid multiple freeze/thaw cycles.
HIST3H3; H3.4; H3/g; H3FT; H3t; histone H3.1t
WB, IHC, IF, IP, ChIP, ChIPseq. Recommended dilutions: WB 1:500 - 1:2000, IHC 1:50 - 1:200, IF 1:50 - 1:200, IP 1:50 - 1:200, CHIP 1:20 - 1:50, CHIPseq 1:20 - 1:50