Histone H3K4ac (Acetyl H3K4) Polyclonal Antibody

Background
Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.

Description
Histone H3K4ac (Acetyl H3K4) Polyclonal Antibody. Unconjugated. Raised in: Rabbit.

Formulation
PBS with 0.02% sodium azide,50% glycerol, pH7.3.

Specificity
Human, Mouse, Rat, Broad Range

Isotype
IgG

Uniprot ID
Q16695

Purification
Affinity Purified

Immunogen
A synthetic acetylated peptide around K4 of human Histone H3 (NP_003484.1).

Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.

Alternative Names
H3.4; H3/g; H3FT; H3t; HIST3H3; Histone H3; HIST1H3A

Application
WB, IF, ChIP; Recommended dilution: WB 1:500 - 1:2000, IF 1:50 - 1:100, ChIP 1:50 - 1:200