BackgroundHistones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H3 family. Transcripts from this gene lack polyA tails; instead, they contain a palindromic termination element. This gene is located separately from the other H3 genes that are in the histone gene cluster on chromosome 6p22-p21. 3.
DescriptionHistone H3K14me2 (H3K14 Dimethyl) Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationPBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SpecificityHuman, Mouse, Rat, Broad Range
IsotypeIgG
Uniprot IDQ16695
PurificationAffinity Purified
ImmunogenA synthetic dimethylated peptide around K14 of human Histone H3 (NP_003520.1)
StorageShipped at 4°C. Upon receipt, store at -20°C. Avoid repeated freeze.
Alternative NamesH3t, H3.4, H3/g, H3FT
ApplicationWB, IF, IP, ChIP, ChIP-seq