BackgroundModulation of chromatin structure via histone modification plays an important role in the regulation of transcription in eukaryotes. Euchromatin, or loosely packed chromatin, is associated with gene expression, whereas tightly coiled chromatin, or heterochromatin, is associated with gene silencing.
DescriptionEpiGentek's Antibody Panel Packs provide a convenient way to investigate a panel of modifications using a collection of select antibodies. The Histone H3 Acetylation Antibody Panel Pack I is a complete set of 4 vials for the investigation of specific site modifications, plus a bonus vial of secondary antibody is also included:
StorageVaries. Please see user guide for recommended storage conditions for each antibody.
Dreval K et. al. (March 2019). HDAC1 negatively regulates selective mitotic chromatin binding of the Notch effector RBPJ in a KDM5A-dependent manner. Nucleic Acids Res.