BackgroundHistone proteins (H2A, H2B, H3, and H4) are the core components of a nucleosome and compact DNA into chromatin. Transcription regulation is affected depending on the availability of the chromatin structure, adjusted by post-translational modifications to histones ? such as histone acetylation ? and remodeling of nucleosomes. Histone acetyltransferases (HATs) act to acetylate histone H2A at lysine 5.
DescriptionHistone H2AK5ac (Acetyl H2AK5) Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationPBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Specificity Broad Range, Human, Mouse, Rat
IsotypeIgG
Uniprot IDP0C0S8
PurificationAffinity Purified
ImmunogenA synthetic acetylated peptide around K5 of human Histone H2A (NP_003508.1).
StorageShipped at 4°C. Upon receipt, store at -20°C. Avoid repeated freeze.
Alternative NamesHIST1H2AI; H2A/c; H2AFC; histone H2A type 1
ApplicationWB, IF