BackgroundCore component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling.
DescriptionHistone H2A.J Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationPreservative: 0.1mol/L NaCl, 15mmol/L NaN3, PH7.2.
SpecificityHuman, Mouse
IsotypeIgG
Uniprot IDQ9BTM1
PurificationProtein G purified
ImmunogenRecombinant Human Histone H2A.J protein (2-129AA)
StorageShipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.
Alternative NamesH2AFJ
ApplicationELISA, WB, IHC; Recommended dilution:WB:1:1000-1:5000, IHC:1:20-1:200