BackgroundHistone deacetylases (HDACs) play a critical role in transcriptional repression of gene expression in eukaryotic cells through catalyzing the hydrolytic removal of acetyl groups from histone lysine residues. Three distinct families of HDACs have been described, comprising a group of at least 20 proteins in humans. HDAC6 is a class II histone deacetylase.
DescriptionMouse monoclonal antibody raised against a full-length recombinant HDAC6, clone 3A6.
Size 100 µg
PurificationProtein A purified
ImmunogenHDAC6 (AAH13737, 1 a.a. ~ 1064 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Cross ReactivityHuman
IsotypeIgG1 Kappa
FormulationIn 1x PBS, pH 7.2
StorageAliquot and store at -20ºC or lower. Avoid repeated freezing and thawing. Multiple freeze/thaw cycles may result in decreased performance.
Handling RecommendationsFor maximum recovery of the products, centrifuge the vial prior to opening the cap.
Alternative NamesFLJ16239 antibody, HD 6 antibody, Histone deacetylase 6 (HD6) antibody, JM 21 antibody, KIAA0901 antibody, OTTHUMP00000032398 antibody, OTTHUMP00000197663 antibody
Applications & Suggested Dilutions*Western Blot: 0.5-1 µg/mlELISA: 0.25-1 µg/ml*The end user is responsible for determining optimal working dilutions.
Quality ControlWestern Blot detection against Immunogen (143.04 KDa).
Note: This item was formerly catalog no. ABB-4006 (ABB4006)
Applications
Western Blot
Applicable
ELISA
Immunohistochemistry (IHC)