Histone H3 combines with Histone H4 to form the H3/H4 tetramer. Two H2A/H2B heterodimers interact with an H3/H4 tetramer to form the histone octamer (1,2). Histone H4 is also modified by various enzymes and can act as a substrate for them. These modifications have been shown to be important in gene regulation.
Molecular Weight (kDa)
20 mM sodium phosphate, 300 mM NaCl, 1 mM EDTA
Expressed in E.coli expression system
Storage Temp & Conditions
Store at -20°C. Aliquot to avoid repeated freezing and thawing.
Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array.