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H4 Protein

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Expressed In: E. Coli
Protein Species: Human
Research Area: Unmodified Histone
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Catalog No.SizePriceQty
E35005-150 µgView
Product Overview

Description
Histone H3 combines with Histone H4 to form the H3/H4 tetramer. Two H2A/H2B heterodimers interact with an H3/H4 tetramer to form the histone octamer (1,2). Histone H4 is also modified by various enzymes and can act as a substrate for them. These modifications have been shown to be important in gene regulation.

Molecular Weight (kDa)
11.2 kDa

Formulation
20 mM sodium phosphate, 300 mM NaCl, 1 mM EDTA

Source
Expressed in E.coli expression system

Size
50 µg

Storage Temp & Conditions
Store at -20°C. Aliquot to avoid repeated freezing and thawing.

Purification Notes
SDS-PAGE purified.

Application Notes
Enzyme-linked Immunoabsorbent Assay; Western Blot (Recombinant protein); Antibody Production; Protein Array.

User Guide & MSDS

[User Guide]*
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Product Citations

Morishita M et. al. (December 2014). In vitro histone lysine methylation by NSD1, NSD2/MMSET/WHSC1, and NSD3/WHSC1L. BMC Struct Biol. 14(1):25.

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