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DTT Solution


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Reagent Type: Other
100% Guarantee: 6 months
Catalog No.SizePriceQty
R-1104-11 ml, 500 mMView
Product Overview

DTT, also known as Cleland's Reagent, is a particularly strong reducing agent, owing to its high conformational proprensity to form a six member ring with an internal disulfide bond.  It has a redox potential of -0.33 V @ pH 7. It is used  for many protein research applications, including reducing polyacrylamide electrophoresis (SDS-PAGE). The 500 mM stock solution  can be directly used to achieve the amount of reducing agent required for your specific application.

Molecular Weight (kDa)
154 kDa

10 mM phosphate buffered saline, pH 7.4

500 mM, 1 ml

Storage Temp & Conditions
>6 months at 4°C. 

Application Notes
Used in biochemistry and various sample preparation applications, works to reduce dissulfide bridges, protects biomolecules, and denatures proteins before electrophoresis analysis (SDS-PAGE). 1-10 mM to maintain reduced proteins in solution, 50-100 mM for complete reduction for electrophoresis.

User Guide & MSDS

[User Guide]*
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