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Introduction to Epigenetics

DNA Replication & Transcription Antibodies

DNA replication is the process by which DNA is duplicated or copied prior to cell division, and which allows the daughter cell to retain a set of its own genetic material. During this process, the two DNA strands are unwound by helicases forming replication forks, and DNA is copied by DNA polymerases to form daughter DNA strands. In eukaryotic cells, the nucleosomes at replication forks must be disassembled and then assembled back. DNA replication progresses by duplication of the DNA at several replication origins. DNA replication follows a semiconservative model, where each daughter cell retains an original parental DNA strand and a newly synthesized daughter strand.

Transcription factors are DNA-binding proteins that regulate gene expression. They can possess more than one DNA-binding domain and may operate alone or form homodimers and heterodimers. After transcription factor binding to DNA, these proteins promote or inhibit RNA polymerase recruitment, thus are considered either activators or repressors. In addition, transcription factors can recruit coactivators and corepressors, or may catalyze histone acetylation and deacetylation. When triggered by environmental or biological stimuli, transcription factors can operate downstream of signaling cascades to alter the expression of target genes. Some transcription factors require ligand binding since this can cause nuclear translocation and variations in the binding affinities for DNA and cofactors. During development, a variety of stimuli can cause transcription factors to upregulate or downregulate gene expression at certain times to ensure proper growth. Transcription factors can also act as oncogenes or tumor suppressors and have been linked to various cancers. Hence, therapeutic approaches in cancer therapy often involve targeting transcription factor families.
Result Pages:  1  2  3  4  5 ...  [Next >>]  Displaying 1 to 20 (of 1634 products)
CIART Polyclonal Antibody, FITC Conjugated
CIART Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Transcription Factors
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A58572-05050 µg $256.00 Add to Cart
A58572-100100 µg $359.00 Add to Cart
Antibodies
CIART Polyclonal Antibody, HRP Conjugated
CIART Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Transcription Factors
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A58573-05050 µg $256.00 Add to Cart
A58573-100100 µg $359.00 Add to Cart
Antibodies
CINP Polyclonal Antibody
CINP Polyclonal Antibody

Application: ELISA
Areas of Research: DNA Replication
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A51229-02020 µg $59.00 Add to Cart
A51229-05050 µg $256.00 Add to Cart
A51229-100100 µg $359.00 Add to Cart
Antibodies
CINP Polyclonal Antibody, Biotin Conjugated
CINP Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: DNA Replication
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A51232-05050 µg $256.00 Add to Cart
A51232-100100 µg $359.00 Add to Cart
Antibodies
CINP Polyclonal Antibody, FITC Conjugated
CINP Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: DNA Replication
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A51231-05050 µg $256.00 Add to Cart
A51231-100100 µg $359.00 Add to Cart
Antibodies
CINP Polyclonal Antibody, HRP Conjugated
CINP Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: DNA Replication
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A51230-05050 µg $256.00 Add to Cart
A51230-100100 µg $359.00 Add to Cart
Antibodies
CIPC Polyclonal Antibody
CIPC Polyclonal Antibody

Application: ELISA, IHC, WB
Areas of Research: Transcription Factors
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human, Mouse
Trial Size Available: Yes
A67674-02020 µg $59.00 Add to Cart
A67674-05050 µg $256.00 Add to Cart
A67674-100100 µg $359.00 Add to Cart
Antibodies
CIPC Polyclonal Antibody, Biotin Conjugated
CIPC Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Transcription Factors
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A67677-05050 µg $256.00 Add to Cart
A67677-100100 µg $359.00 Add to Cart
Antibodies
CIPC Polyclonal Antibody, FITC Conjugated
CIPC Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Transcription Factors
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A67676-05050 µg $256.00 Add to Cart
A67676-100100 µg $359.00 Add to Cart
Antibodies
CIPC Polyclonal Antibody, HRP Conjugated
CIPC Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Transcription Factors
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A67675-05050 µg $256.00 Add to Cart
A67675-100100 µg $359.00 Add to Cart
Antibodies
CNBP Polyclonal Antibody
CNBP Polyclonal Antibody

Application: ELISA, IHC
Areas of Research: Transcription Factors
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A50129-02020 µg $59.00 Add to Cart
A50129-05050 µg $256.00 Add to Cart
A50129-100100 µg $359.00 Add to Cart
Antibodies
CNBP Polyclonal Antibody, Biotin Conjugated
CNBP Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Transcription Factors
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A50132-05050 µg $256.00 Add to Cart
A50132-100100 µg $359.00 Add to Cart
Antibodies
CNBP Polyclonal Antibody, FITC Conjugated
CNBP Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Transcription Factors
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A50131-05050 µg $256.00 Add to Cart
A50131-100100 µg $359.00 Add to Cart
Antibodies
CNBP Polyclonal Antibody, HRP Conjugated
CNBP Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Transcription Factors
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A50130-05050 µg $256.00 Add to Cart
A50130-100100 µg $359.00 Add to Cart
Antibodies
CREB1 Polyclonal Antibody
CREB1 Polyclonal Antibody

Application: ELISA, IHC, WB
Areas of Research: Transcription Factors
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human, Mouse
Trial Size Available: Yes
A52845-02020 µg $59.00 Add to Cart
A52845-05050 µg $256.00 Add to Cart
A52845-100100 µg $359.00 Add to Cart
Antibodies
CREB1 Polyclonal Antibody, Biotin Conjugated
CREB1 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Transcription Factors
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A52846-05050 µg $256.00 Add to Cart
A52846-100100 µg $359.00 Add to Cart
Antibodies
CREB1 Polyclonal Antibody, FITC Conjugated
CREB1 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: Transcription Factors
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A52848-05050 µg $256.00 Add to Cart
A52848-100100 µg $359.00 Add to Cart
Antibodies
CREB1 Polyclonal Antibody, HRP Conjugated
CREB1 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: Transcription Factors
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A52847-05050 µg $256.00 Add to Cart
A52847-100100 µg $359.00 Add to Cart
Antibodies
CRIP2 Polyclonal Antibody
CRIP2 Polyclonal Antibody

Application: ELISA
Areas of Research: Transcription Factors
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A57369-02020 µg $59.00 Add to Cart
A57369-05050 µg $256.00 Add to Cart
A57369-100100 µg $359.00 Add to Cart
Antibodies
CRIP2 Polyclonal Antibody, Biotin Conjugated
CRIP2 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: Transcription Factors
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A57372-05050 µg $256.00 Add to Cart
A57372-100100 µg $359.00 Add to Cart
Antibodies
Result Pages:  1  2  3  4  5 ...  [Next >>]  Displaying 1 to 20 (of 1634 products)
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