DNA methylation and demethylation are major epigenetic mechanisms that modulate gene expression in both eukaryotes and prokaryotes. Epigenetic modification 5-methylcytosine (5mC), considered the hallmark of gene silencing, has been implicated to play an important role in regulating several cellular and developmental processes, including mediating carcinogenic transformation of healthy cells. 5-hydroxymethylcytosine (5hmC) derived from enzymatic oxidization of 5mC has also been associated with many biological processes, including the pluripotency of embryonic stem cells, neuron development, and tumorigenesis in mammals.
What makes buying antibodies from EpiGentek different?
At EpiGentek, we supply a collection of over 20,000 individual high-quality antibodies for our customers to ensure that our research customers find exactly what they need for their studies. In addition, we offer a variety of other benefits to help our customers in terms of affordability, convenience, and reliability. See why working with EpiGentek for your antibodies is the right choice:
No Shipping & Handling Costs: we’ve waived all shipping and handling fees on our antibodies and antibody panel packs when selecting 2-day shipping (trial sizes not applicable).
100% Application Guarantee: your purchased antibodies are covered for 6-months past the date of purchase.
Multiple Conjugates: we carry biotin, FITC and HRP conjugates for nearly all targets.
Trial Sizes Available: 10 & 20 µg options available on over 5,000 antibodies in our catalog.