DNA Methylation Antibodies

DNA methylation is the most widely studied epigenetic mechanism that regulates gene expression, thereby affecting cell function. Aberrant DNA methylation is prevalent in many diseases, particularly cancer. EpigenTek's well-characterized and highly validated DNA methylation antibodies and DNA demethylation antibodies may help to increase researchers' understanding of DNA methylation and its involvement in diseases, as well as cell cycle regulation and embryonic development.

DNA methylation and demethylation antibodies are used in various techniques, including dot blot (DB), enzyme-linked immunosorbent assay (ELISA), methylated DNA immunoprecipitation (MeDIP), immunofluorescence (IF), and immunohistochemistry (IHC), to identify and quantify methylated/demethylated DNA regions in a genome-wide scale. These techniques allow researchers to study the distribution of DNA modification across different genes, regions, and cell types, which can provide insight into how this process is involved in regulating gene expression and its role in various biological activities, such as development, aging, and disease.

In addition to their utility in identifying and quantifying regions that have undergone DNA methylation and demethylation, these antibodies can also be used to study the enzymes and proteins that facilitate the modification process.

• No Shipping & Handling Costs: we’ve waived all shipping and handling fees on our antibodies and antibody panel packs when selecting 2-day shipping (trial sizes not applicable).
• 100% Application Guarantee: your purchased antibodies are covered for 6-months past the date of purchase.
• Multiple Conjugates: we carry biotin, FITC and HRP conjugates for nearly all targets.
• Trial Sizes Available: 10 & 20 µl options available for thousands of antibodies in our catalog