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DNA Damage & Repair Antibodies

Cells undergo DNA damage constantly from exogenous and endogenous sources. Some of these sources include UV-light, ionizing radiation, alkylating agents and other environmental DNA damaging agents, as well as other sources derived spontaneously from cellular metabolism, such as reactive oxygen species. DNA damaging agents can cause a number of DNA lesions, including adducts, apurinic/apyrimidinic sites (AP sites), single-strand and double-strand DNA breaks. Left unrepaired, these DNA lesions could result in mutations, senescence, or induction of cell death which could lead to the development of neurodegeneration, cancer and other diseases.

In order to maintain genomic integrity, cells have developed the DNA damage response (DDR) pathway which allows cells to recognize the DNA damage and facilitate recruitment and activation of DNA repair proteins. Members of the phosphatidyl-inositol 3-kinase like protein kinase (PIKK) family, such as ATM, ATR and DNA-PK, are involved in this response, as well as a few members of the poly (ADP-ribose) polymerase (PARP) family.

Several DNA repair pathways exist to correct the DNA lesions depending on the particular form of DNA damage. For instance, the base excision repair (BER) and the mismatch repair (MMR) pathways mend damaged or mispaired DNA bases by excising the damaged base or by replacing mispaired bases with correct ones. Nucleotide excision repair (NER) fixes DNA lesions such as intrastrand crosslinks by removing a larger oligonucleotide DNA fragment; while double-strand breaks are generally repaired by non-homology end-joining (NHEJ) or by homology-directed repair (HDR).
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RAD9B Polyclonal Antibody
RAD9B Polyclonal Antibody

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A68947-02020 µg $99.00 Add to Cart
A68947-05050 µg $249.00 Add to Cart
A68947-100100 µg $399.00 Add to Cart
Antibodies
RAD9B Polyclonal Antibody, Biotin Conjugated
RAD9B Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A68950-05050 µg $249.00 Add to Cart
A68950-100100 µg $399.00 Add to Cart
Antibodies
RAD9B Polyclonal Antibody, FITC Conjugated
RAD9B Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A68949-05050 µg $249.00 Add to Cart
A68949-100100 µg $399.00 Add to Cart
Antibodies
RAD9B Polyclonal Antibody, HRP Conjugated
RAD9B Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A68948-05050 µg $249.00 Add to Cart
A68948-100100 µg $399.00 Add to Cart
Antibodies
SHPRH Polyclonal Antibody
SHPRH Polyclonal Antibody

Application: ELISA, IF, IHC
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A69879-02020 µg $99.00 Add to Cart
A69879-05050 µg $249.00 Add to Cart
A69879-100100 µg $399.00 Add to Cart
Antibodies
SHPRH Polyclonal Antibody, Biotin Conjugated
SHPRH Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A69882-05050 µg $249.00 Add to Cart
A69882-100100 µg $399.00 Add to Cart
Antibodies
SHPRH Polyclonal Antibody, FITC Conjugated
SHPRH Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A69881-05050 µg $249.00 Add to Cart
A69881-100100 µg $399.00 Add to Cart
Antibodies
SHPRH Polyclonal Antibody, HRP Conjugated
SHPRH Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A69880-05050 µg $249.00 Add to Cart
A69880-100100 µg $399.00 Add to Cart
Antibodies
SMC5 Polyclonal Antibody
SMC5 Polyclonal Antibody

Application: ELISA, WB
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A69999-02020 µg $99.00 Add to Cart
A69999-05050 µg $249.00 Add to Cart
A69999-100100 µg $399.00 Add to Cart
Antibodies
SMC5 Polyclonal Antibody, Biotin Conjugated
SMC5 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A70002-05050 µg $249.00 Add to Cart
A70002-100100 µg $399.00 Add to Cart
Antibodies
SMC5 Polyclonal Antibody, FITC Conjugated
SMC5 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A70001-05050 µg $249.00 Add to Cart
A70001-100100 µg $399.00 Add to Cart
Antibodies
SMC5 Polyclonal Antibody, HRP Conjugated
SMC5 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A70000-05050 µg $249.00 Add to Cart
A70000-100100 µg $399.00 Add to Cart
Antibodies
SMUG1 Polyclonal Antibody
SMUG1 Polyclonal Antibody

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A61054-02020 µg $99.00 Add to Cart
A61054-05050 µg $256.00 Add to Cart
A61054-100100 µg $359.00 Add to Cart
Antibodies
SMUG1 Polyclonal Antibody, Biotin Conjugated
SMUG1 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A61055-05050 µg $256.00 Add to Cart
A61055-100100 µg $359.00 Add to Cart
Antibodies
SMUG1 Polyclonal Antibody, FITC Conjugated
SMUG1 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A61056-05050 µg $256.00 Add to Cart
A61056-100100 µg $359.00 Add to Cart
Antibodies
SMUG1 Polyclonal Antibody, HRP Conjugated
SMUG1 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A61057-05050 µg $256.00 Add to Cart
A61057-100100 µg $359.00 Add to Cart
Antibodies
SPRTN Polyclonal Antibody
SPRTN Polyclonal Antibody

Application: ELISA, IHC
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A61134-02020 µg $99.00 Add to Cart
A61134-05050 µg $256.00 Add to Cart
A61134-100100 µg $359.00 Add to Cart
Antibodies
SPRTN Polyclonal Antibody, Biotin Conjugated
SPRTN Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A61135-05050 µg $256.00 Add to Cart
A61135-100100 µg $359.00 Add to Cart
Antibodies
SPRTN Polyclonal Antibody, FITC Conjugated
SPRTN Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A61136-05050 µg $256.00 Add to Cart
A61136-100100 µg $359.00 Add to Cart
Antibodies
SPRTN Polyclonal Antibody, HRP Conjugated
SPRTN Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A61137-05050 µg $256.00 Add to Cart
A61137-100100 µg $359.00 Add to Cart
Antibodies
Result Pages: [<< Prev]  ... 6  7  8  9  [Next >>]  Displaying 121 to 140 (of 169 products)
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