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DNA Damage & Repair Antibodies

Cells undergo DNA damage constantly from exogenous and endogenous sources. Some of these sources include UV-light, ionizing radiation, alkylating agents and other environmental DNA damaging agents, as well as other sources derived spontaneously from cellular metabolism, such as reactive oxygen species. DNA damaging agents can cause a number of DNA lesions, including adducts, apurinic/apyrimidinic sites (AP sites), single-strand and double-strand DNA breaks. Left unrepaired, these DNA lesions could result in mutations, senescence, or induction of cell death which could lead to the development of neurodegeneration, cancer and other diseases.

In order to maintain genomic integrity, cells have developed the DNA damage response (DDR) pathway which allows cells to recognize the DNA damage and facilitate recruitment and activation of DNA repair proteins. Members of the phosphatidyl-inositol 3-kinase like protein kinase (PIKK) family, such as ATM, ATR and DNA-PK, are involved in this response, as well as a few members of the poly (ADP-ribose) polymerase (PARP) family.

Several DNA repair pathways exist to correct the DNA lesions depending on the particular form of DNA damage. For instance, the base excision repair (BER) and the mismatch repair (MMR) pathways mend damaged or mispaired DNA bases by excising the damaged base or by replacing mispaired bases with correct ones. Nucleotide excision repair (NER) fixes DNA lesions such as intrastrand crosslinks by removing a larger oligonucleotide DNA fragment; while double-strand breaks are generally repaired by non-homology end-joining (NHEJ) or by homology-directed repair (HDR).
Result Pages: [<< Prev]   1  2  3  4  5 ...  [Next >>]  Displaying 61 to 80 (of 169 products)
MND1 Polyclonal Antibody, Biotin Conjugated
MND1 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A67665-05050 µgView
A67665-100100 µgView
Antibodies
MND1 Polyclonal Antibody, FITC Conjugated
MND1 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A67664-05050 µgView
A67664-100100 µgView
Antibodies
MND1 Polyclonal Antibody, HRP Conjugated
MND1 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A67663-05050 µgView
A67663-100100 µgView
Antibodies
MPG Polyclonal Antibody
MPG Polyclonal Antibody

Application: IF, WB
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Affinity Purified
Reactivity: Human, Mouse, Rat
A-2718-05050 µlView
A-2718-100100 µlView
Antibodies
MSH4 Polyclonal Antibody
MSH4 Polyclonal Antibody

Application: ELISA, IF, IHC, WB
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human, Mouse
Trial Size Available: Yes
A62986-02020 µgView
A62986-05050 µgView
A62986-100100 µgView
Antibodies
MSH4 Polyclonal Antibody, Biotin Conjugated
MSH4 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A62989-05050 µgView
A62989-100100 µgView
Antibodies
MSH4 Polyclonal Antibody, FITC Conjugated
MSH4 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A62988-05050 µgView
A62988-100100 µgView
Antibodies
MSH4 Polyclonal Antibody, HRP Conjugated
MSH4 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A62987-05050 µgView
A62987-100100 µgView
Antibodies
MSH6 Polyclonal Antibody
MSH6 Polyclonal Antibody

Application: ELISA, IF, IHC
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A50386-02020 µgView
A50386-05050 µgView
A50386-100100 µgView
Antibodies
MSH6 Polyclonal Antibody
MSH6 Polyclonal Antibody

Application: IF, IHC, WB
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Affinity Purified
Reactivity: Human, Mouse, Rat
A-6702-05050 µlView
A-6702-100100 µlView
Antibodies
MSH6 Polyclonal Antibody, Biotin Conjugated
MSH6 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A50389-05050 µgView
A50389-100100 µgView
Antibodies
MSH6 Polyclonal Antibody, FITC Conjugated
MSH6 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A50388-05050 µgView
A50388-100100 µgView
Antibodies
MSH6 Polyclonal Antibody, HRP Conjugated
MSH6 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A50387-05050 µgView
A50387-100100 µgView
Antibodies
mutT Polyclonal Antibody
mutT Polyclonal Antibody

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Escherichia coli
Trial Size Available: Yes
A64466-02020 µgView
A64466-05050 µgView
A64466-100100 µgView
Antibodies
mutT Polyclonal Antibody, Biotin Conjugated
mutT Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Escherichia coli
A64469-05050 µgView
A64469-100100 µgView
Antibodies
mutT Polyclonal Antibody, FITC Conjugated
mutT Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Escherichia coli
A64468-05050 µgView
A64468-100100 µgView
Antibodies
mutT Polyclonal Antibody, HRP Conjugated
mutT Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Escherichia coli
A64467-05050 µgView
A64467-100100 µgView
Antibodies
NABP1 Polyclonal Antibody
NABP1 Polyclonal Antibody

Application: ELISA, WB
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A55838-02020 µgView
A55838-05050 µgView
A55838-100100 µgView
Antibodies
NABP1 Polyclonal Antibody, Biotin Conjugated
NABP1 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A55841-05050 µgView
A55841-100100 µgView
Antibodies
NABP1 Polyclonal Antibody, FITC Conjugated
NABP1 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A55840-05050 µgView
A55840-100100 µgView
Antibodies
Result Pages: [<< Prev]   1  2  3  4  5 ...  [Next >>]  Displaying 61 to 80 (of 169 products)
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