Epigentek Home
 Find Your Distributor      
 
Refine Your Results
DNA Methylation Antibody Panel Pack

DNA Damage & Repair Antibodies

Cells undergo DNA damage constantly from exogenous and endogenous sources. Some of these sources include UV-light, ionizing radiation, alkylating agents and other environmental DNA damaging agents, as well as other sources derived spontaneously from cellular metabolism, such as reactive oxygen species. DNA damaging agents can cause a number of DNA lesions, including adducts, apurinic/apyrimidinic sites (AP sites), single-strand and double-strand DNA breaks. Left unrepaired, these DNA lesions could result in mutations, senescence, or induction of cell death which could lead to the development of neurodegeneration, cancer and other diseases.

In order to maintain genomic integrity, cells have developed the DNA damage response (DDR) pathway which allows cells to recognize the DNA damage and facilitate recruitment and activation of DNA repair proteins. Members of the phosphatidyl-inositol 3-kinase like protein kinase (PIKK) family, such as ATM, ATR and DNA-PK, are involved in this response, as well as a few members of the poly (ADP-ribose) polymerase (PARP) family.

Several DNA repair pathways exist to correct the DNA lesions depending on the particular form of DNA damage. For instance, the base excision repair (BER) and the mismatch repair (MMR) pathways mend damaged or mispaired DNA bases by excising the damaged base or by replacing mispaired bases with correct ones. Nucleotide excision repair (NER) fixes DNA lesions such as intrastrand crosslinks by removing a larger oligonucleotide DNA fragment; while double-strand breaks are generally repaired by non-homology end-joining (NHEJ) or by homology-directed repair (HDR).
Result Pages:  1  2  3  4  5 ...  [Next >>]  Displaying 1 to 20 (of 169 products)
Image Description Cat. No. Size Price
8-Hydroxyguanosine (8-OHG) Polyclonal Antibody
8-Hydroxyguanosine (8-OHG) Polyclonal Antibody

Application: ELISA, IH
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Goat
Isotype: IgG
Purification: Serum
Reactivity: Broad Range
A-6300-10.1 mlViewDiscontinued
Antibodies
APEX1 Polyclonal Antibody
APEX1 Polyclonal Antibody

Application: ChIP, ELISA, IHC, WB
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human, Mouse
Trial Size Available: Yes
A68301-02020 µgView
A68301-05050 µgView
A68301-100100 µgView
Antibodies
APEX1 Polyclonal Antibody, Biotin Conjugated
APEX1 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A53393-05050 µgView
A53393-100100 µgView
Antibodies
APEX1 Polyclonal Antibody, FITC Conjugated
APEX1 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A53394-05050 µgView
A53394-100100 µgView
Antibodies
APEX1 Polyclonal Antibody, HRP Conjugated
APEX1 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A53395-05050 µgView
A53395-100100 µgView
Antibodies
BRCA1 Polyclonal Antibody
BRCA1 Polyclonal Antibody

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A54101-02020 µgView
A54101-05050 µgView
A54101-100100 µgView
Antibodies
BRCA1 Polyclonal Antibody, Biotin Conjugated
BRCA1 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A54104-05050 µgView
A54104-100100 µgView
Antibodies
BRCA1 Polyclonal Antibody, FITC Conjugated
BRCA1 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A54103-05050 µgView
A54103-100100 µgView
Antibodies
BRCA1 Polyclonal Antibody, HRP Conjugated
BRCA1 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A54102-05050 µgView
A54102-100100 µgView
Antibodies
BRCC3 Polyclonal Antibody
BRCC3 Polyclonal Antibody

Application: ELISA, IHC, WB
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A54460-02020 µgView
A54460-05050 µgView
A54460-100100 µgView
Antibodies
BRCC3 Polyclonal Antibody, Biotin Conjugated
BRCC3 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A54461-05050 µgView
A54461-100100 µgView
Antibodies
BRCC3 Polyclonal Antibody, FITC Conjugated
BRCC3 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A54463-05050 µgView
A54463-100100 µgView
Antibodies
BRCC3 Polyclonal Antibody, HRP Conjugated
BRCC3 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A54462-05050 µgView
A54462-100100 µgView
Antibodies
CETN2 Polyclonal Antibody
CETN2 Polyclonal Antibody

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A54898-02020 µgView
A54898-05050 µgView
A54898-100100 µgView
Antibodies
CETN2 Polyclonal Antibody, Biotin Conjugated
CETN2 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A54895-05050 µgView
A54895-100100 µgView
Antibodies
CETN2 Polyclonal Antibody, FITC Conjugated
CETN2 Polyclonal Antibody, FITC Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: FITC
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A54896-05050 µgView
A54896-100100 µgView
Antibodies
CETN2 Polyclonal Antibody, HRP Conjugated
CETN2 Polyclonal Antibody, HRP Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: HRP
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A54897-05050 µgView
A54897-100100 µgView
Antibodies
ERCC6L Polyclonal Antibody
ERCC6L Polyclonal Antibody

Application: WB
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Affinity Purified
Reactivity: Human
A-2735-05050 µlView
A-2735-100100 µlView
Antibodies
ERCC6L2 Polyclonal Antibody
ERCC6L2 Polyclonal Antibody

Application: ELISA, IHC
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
Trial Size Available: Yes
A62190-02020 µgView
A62190-05050 µgView
A62190-100100 µgView
Antibodies
ERCC6L2 Polyclonal Antibody, Biotin Conjugated
ERCC6L2 Polyclonal Antibody, Biotin Conjugated

Application: ELISA
Areas of Research: DNA Damage & Repair
Clonality: Polyclonal
Conjugate: Biotin
Host: Rabbit
Isotype: IgG
Purification: >95%, Protein G Purified
Reactivity: Human
A62193-05050 µgView
A62193-100100 µgView
Antibodies
Result Pages:  1  2  3  4  5 ...  [Next >>]  Displaying 1 to 20 (of 169 products)
Epigentek is an epigenetics company that specializes in epigenetic kits, antibodies, reagents, and services for epigenetic research in DNA methylation, histone modification, and chromatin studies. Terms & Conditions | Privacy Policy | Site Map
Copyright © 2018 Epigentek Group Inc. All rights reserved.