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Chromatin & Transcription

Chromatin & Transcription

Chromatin structures are regulated by various mechanisms including histone modification and chromatin remodeling, which involve the binding of transcription factors. By using tools such as chromatin immunoprecipitation, it is possible to gain further insight into the dynamic interactions between transcription proteins and components of chromatin, and to ultimately understand their roles in cellular functions such as gene transcription and epigenetic silencing.
General Chromatin Immunoprecipitation
Chromatin immunoprecipitation (ChIP) is an antibody-based method used for determining the location of DNA binding sites on the genome for a particular protein of interest. This technique is a convenient means for studying protein-DNA interactions that occur inside the nucleus of cells and for understanding cellular processes. Downstream applications of ChIP include ChIP-sequencing, ChIP-PCR, and ChIP-on-chip (microarrays).

In Vitro Protein-DNA Interaction
Measurement of direct interactions between protein and DNA in vitro has an advantage in analyzing the binding of different transcription factors to specific DNA consensus sequences located in the gene promoters. By investigating protein-DNA interaction in vitro, it is possible to identify the genetic targets of DNA, which leads to a better understanding of cellular processes.

Methyl-Histone Chromatin IP
Chromatin immunoprecipitation is a powerful technique for studying protein-DNA interaction in vivo, and can be coupled with various downstream applications to profile and map histone methylation patterns.

Acetyl-Histone Chromatin IP
Chromatin immunoprecipitation can be used as a tool to identify activated genes associated with acetylated histones, and can be coupled with qualitative and quantitative PCR, MSP, DNA sequencing, and Southern blot as well as DNA microarrays to further profile or map histone acetylation patterns.

Methyl-DNA Binding Protein ChIP
Methyl-CpG-binding domain protein 2 (MBD2) is a member of the MBD protein family and has been shown to catalyze demethylation by direclty removing methyl groups from 5-methylcytosine residues in DNA. Chromatin immunoprecipitation would be useful in the identification of silenced genes associated with MBD2, and can be combined with qualitative and quantitative PCR, MSP, DNA sequencing, DNA microarrays, and Southern blot to profile or map MBD2 binding patterns.

Chromatin Analysis

Result Pages:  1  2  [Next >>]  Displaying 1 to 20 (of 24 products)
Image Description Cat. No. Size Price
ChromaFlash High-Sensitivity ChIP Kit
ChromaFlash High-Sensitivity ChIP Kit

Citations (6)
Input Type: Chromatin
Research Area: Chromatin & Transcription
Target Application: Immunoprecipitation
Vessel Format: 96-Well Plate
P-2027-2424 reactions $255.00 Add to Cart
P-2027-4848 reactions $399.00 Add to Cart
Research Kits
ChromaFlash One-Step Magnetic ChIP Kit
ChromaFlash One-Step Magnetic ChIP Kit

Input Type: Chromatin
Research Area: Chromatin & Transcription
Target Application: Immunoprecipitation
Vessel Format: 96-Well Plate
P-2026-4848 reactions $338.00 Add to Cart
P-2026-9696 reactions $549.00 Add to Cart
Research Kits
EpiNext ChIP-Seq High-Sensitivity Kit (Illumina)
EpiNext ChIP-Seq High-Sensitivity Kit (Illumina)

Citations (1)
Input Type: Chromatin
Research Area: Chromatin & Transcription
Target Application: Immunoprecipitation, Library Construction
Vessel Format: Columns/Tubes
P-2030-1212 reactions $539.00 Add to Cart
P-2030-2424 reactions $999.00 Add to Cart
Research Kits
EpiQuik Acetyl-Histone H3 ChIP Kit
EpiQuik Acetyl-Histone H3 ChIP Kit

Citations (13) | (1)
Input Type: Chromatin
Research Area: Chromatin & Transcription
Target Application: Immunoprecipitation
Vessel Format: 96-Well Plate
P-2010-2424 reactions $338.00 Add to Cart
P-2010-4848 reactions $539.00 Add to Cart
Research Kits
EpiQuik Acetyl-Histone H4 ChIP Kit
EpiQuik Acetyl-Histone H4 ChIP Kit

Citations (2)
Input Type: Chromatin
Research Area: Chromatin & Transcription
Target Application: Immunoprecipitation
Vessel Format: 96-Well Plate
P-2011-2424 reactions $338.00 Add to Cart
P-2011-4848 reactions $539.00 Add to Cart
Research Kits
EpiQuik Chromatin Accessibility and Methylome Sequencing (CAMe-Seq) Kit
EpiQuik Chromatin Accessibility and Methylome Sequencing (CAMe-Seq) Kit

Input Type: Cell Extracts, Chromatin, Unisolated Samples
Research Area: Chromatin & Transcription
Target Application: Sample Modification
Vessel Format: Columns/Tubes
P-1048-4848 assays $648.00 Discontinued
Research Kits
EpiQuik Chromatin Accessibility Assay Kit
EpiQuik Chromatin Accessibility Assay Kit

Citations (3)
Input Type: Cell Extracts, Chromatin, Unisolated Samples
Research Area: Chromatin & Transcription
Target Application: Sample Modification
Vessel Format: Columns/Tubes
P-1047-4848 assays $462.00 Add to Cart
Research Kits
EpiQuik Chromatin Immunoprecipitation (ChIP) Kit
EpiQuik Chromatin Immunoprecipitation (ChIP) Kit

Citations (129) | (1)
Input Type: Chromatin
Research Area: Chromatin & Transcription
Target Application: Immunoprecipitation
Vessel Format: 96-Well Plate
P-2002-124 reactions $234.00 Add to Cart
P-2002-248 reactions $380.00 Add to Cart
Research Kits
EpiQuik General Protein-DNA Binding Assay Kit (Colorimetric)
EpiQuik General Protein-DNA Binding Assay Kit (Colorimetric)

Citations (5)
Input Type: Nuclear Extracts
Research Area: Chromatin & Transcription
Target Application: Activity Measurement
Vessel Format: 96-Well Plate
P-2004-9696 assays $369.00 Add to Cart
Research Kits
EpiQuik General Protein-DNA Binding Assay Kit (Fluorometric)
EpiQuik General Protein-DNA Binding Assay Kit (Fluorometric)

Citations (3)
Input Type: Nuclear Extracts
Research Area: Chromatin & Transcription
Target Application: Activity Measurement
Vessel Format: 96-Well Plate
P-2005-9696 assays $380.00 Add to Cart
Research Kits
EpiQuik Methyl-CpG Binding Domain Protein 2 ChIP Kit
EpiQuik Methyl-CpG Binding Domain Protein 2 ChIP Kit

Input Type: Chromatin
Research Area: Chromatin & Transcription
Target Application: Immunoprecipitation
Vessel Format: 96-Well Plate
P-2017-2424 reactions $380.00 Add to Cart
P-2017-4848 reactions $549.00 Add to Cart
Research Kits
EpiQuik Methyl-Histone H3K27 ChIP Kit
EpiQuik Methyl-Histone H3K27 ChIP Kit

Citations (2)
Input Type: Chromatin
Research Area: Chromatin & Transcription
Target Application: Immunoprecipitation
Vessel Format: 96-Well Plate
P-2015-2424 reactions $380.00 Add to Cart
P-2015-4848 reactions $549.00 Add to Cart
Research Kits
EpiQuik Methyl-Histone H3K4 ChIP Kit
EpiQuik Methyl-Histone H3K4 ChIP Kit

Citations (3)
Input Type: Chromatin
Research Area: Chromatin & Transcription
Target Application: Immunoprecipitation
Vessel Format: 96-Well Plate
P-2007-2424 reactions $318.00 Add to Cart
P-2007-4848 reactions $524.00 Add to Cart
Research Kits
EpiQuik Methyl-Histone H3K9 ChIP Kit
EpiQuik Methyl-Histone H3K9 ChIP Kit

Citations (3)
Input Type: Chromatin
Research Area: Chromatin & Transcription
Target Application: Immunoprecipitation
Vessel Format: 96-Well Plate
P-2006-2424 reactions $338.00 Add to Cart
P-2006-4848 reactions $539.00 Add to Cart
Research Kits
EpiQuik Plant ChIP Kit
EpiQuik Plant ChIP Kit

Citations (48) | (2)
Input Type: Chromatin
Research Area: Chromatin & Transcription
Target Application: Immunoprecipitation
Vessel Format: 96-Well Plate
P-2014-2424 reactions $299.00 Add to Cart
P-2014-4848 reactions $499.00 Add to Cart
Research Kits
EpiQuik Tissue Acetyl-Histone H3 ChIP Kit
EpiQuik Tissue Acetyl-Histone H3 ChIP Kit

Citations (7) | (1)
Input Type: Chromatin
Research Area: Chromatin & Transcription
Target Application: Immunoprecipitation
Vessel Format: 96-Well Plate
P-2012-2424 reactions $338.00 Add to Cart
P-2012-4848 reactions $539.00 Add to Cart
Research Kits
EpiQuik Tissue Acetyl-Histone H4 ChIP Kit
EpiQuik Tissue Acetyl-Histone H4 ChIP Kit

Citations (2)
Input Type: Chromatin
Research Area: Chromatin & Transcription
Target Application: Immunoprecipitation
Vessel Format: 96-Well Plate
P-2013-2424 reactions $338.00 Add to Cart
P-2013-4848 reactions $539.00 Add to Cart
Research Kits
EpiQuik Tissue Chromatin Immunoprecipitation (ChIP) Kit
EpiQuik Tissue Chromatin Immunoprecipitation (ChIP) Kit

Citations (35)
Input Type: Chromatin
Research Area: Chromatin & Transcription
Target Application: Immunoprecipitation
Vessel Format: 96-Well Plate
P-2003-124 reactions $234.00 Add to Cart
P-2003-248 reactions $380.00 Add to Cart
P-2003-396 reactions $559.00 Add to Cart
Research Kits
EpiQuik Tissue Methyl-CpG Binding Domain Protein 2 ChIP Kit
EpiQuik Tissue Methyl-CpG Binding Domain Protein 2 ChIP Kit

Citations (1)
Input Type: Chromatin
Research Area: Chromatin & Transcription
Target Application: Immunoprecipitation
Vessel Format: 96-Well Plate
P-2018-2424 reactions $380.00 Add to Cart
P-2018-4848 reactions $549.00 Add to Cart
Research Kits
EpiQuik Tissue Methyl-Histone H3K27 ChIP Kit
EpiQuik Tissue Methyl-Histone H3K27 ChIP Kit

Citations (1)
Input Type: Chromatin
Research Area: Chromatin & Transcription
Target Application: Immunoprecipitation
Vessel Format: 96-Well Plate
P-2016-2424 reactions $380.00 Add to Cart
P-2016-4848 reactions $549.00 Add to Cart
Research Kits
Result Pages:  1  2  [Next >>]  Displaying 1 to 20 (of 24 products)
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