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ATG16L1 Polyclonal Antibody

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Immunohistochemistry of paraffin-embedded human skin tissue using ATG16L1 Polyclonal Antibody at dilution 1:100
Immunohistochemistry of paraffin-embedded human colon cancer tissue using ATG16L1 Polyclonal Antibody at dilution 1:100
Application: ELISA, IF, IHC
Areas of Research: Apoptosis & Cell Death
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Protein G Purified
Reactivity: Human
Trial Size Available: Yes
100% Guarantee: 6 months
Catalog No.SizePriceQty
A50989-02020 µgView
A50989-05050 µgView
A50989-100100 µgView
Product Overview

Background
Plays an essential role in autophagy: interacts with ATG12-ATG5 to mediate the conjugation of phosphatidylethanolamine (PE) to LC3 (MAP1LC3A, MAP1LC3B or MAP1LC3C), to produce a membrane-bound activated form of LC3 named LC3-II. Thereby, controls the elongation of the nascent autophagosomal membrane.

Description
ATG16L1 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.

Formulation
Liquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, PH 7.4.

Specificity
Human

Isotype
IgG

Uniprot ID
Q676U5

Purification
>95%, Protein G purified

Immunogen
Recombinant Human Autophagy-related protein 16-1 protein (1-607AA)

Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C (short-term) or -80°C (long-term). Avoid repeated freeze.

Alternative Names
Autophagy-related protein 16-1, APG16-like 1, ATG16L1, APG16L

Application
ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:200-1:500

User Guide & MSDS

[User Guide]*
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