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APHA Compound 8


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Application: Enzyme Inhibition
Molecular Weight: 100-500
Research Area: Histone Acetylation
Solubility: DMSO
100% Guarantee: 6 months
Catalog No.SizePriceQty
M45003-11 mg $162.00  Discontinued
Availability: Discontinued 
Product Overview

Alternative Names

APHA Compound 8 is a potent novel hydroxamate HDAC inhibitor, is in the same structural class as SAHA, an investigational drug standard currently in clinical trial. The IC50 for mouse HDAC1 is 0.5 µM. In a separate study, significant inhibition was found in the proliferation of MEL cells at 24 µM and differentiation, assayed as the accumulation of hemoglobin, at 5 µM.

CAS Number

Chemical Formula

Molecular Weight

1 mg



Soluble in DMSO: >10 mg/mL

Storage Temp

User Guide & MSDS

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