Alternative Names3-(1-Methyl-4-phenylacetyl-1H-2-pyrrolyl)-N-hydroxy-2-propenamide
DescriptionAPHA Compound 8 is a potent novel hydroxamate HDAC inhibitor, is in the same structural class as SAHA, an investigational drug standard currently in clinical trial. The IC50 for mouse HDAC1 is 0.5 µM. In a separate study, significant inhibition was found in the proliferation of MEL cells at 24 µM and differentiation, assayed as the accumulation of hemoglobin, at 5 µM.CAS Number676599-90-9Chemical FormulaC16H16N2O3Molecular Weight284.31
Size1 mgPurity>98%SolubilitySoluble in DMSO: >10 mg/mLStorage Temp-20°C