BackgroundPCAF (P300/CBP-associated factor) has been identified in several species and is a nuclear histone acetylase which plays a role in the regulation of transcription, cell cycle progression and differentiation. Human PCAF is a ubiquitous protein member of the GCN5-related histone acetyltransferas superfamily. PCAF interacts with P300 and CBP transcriptional cofactors and acetylates all 4 core-histones. Also, it has been also shown to acetylate various other proteins, including the transcription factors p53 and p65.
DescriptionPCAF Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300. 50% Glycerol, 0.01M PBS, pH 7.4.
SpecificityHuman
IsotypeIgG
Uniprot IDQ92831
PurificationProtein G purified
ImmunogenRecombinant Human Histone acetyltransferase KAT2B protein (767-832AA)
StorageShipped at 4°C (Blue Ice)
Alternative NamesCAF antibody, CREBBP associated factor antibody, GCN5 antibody, GCN5L antibody, GCN5L1 antibody, Histone acetylase PCAF antibody, Histone acetyltransferase KAT2B antibody, Histone acetyltransferase PCAF antibody, K(lysine) acetyltransferase 2B antibody, KAT2B antibody, Lysine acetyltransferase 2B antibody, P antibody, p300/CBP associated factor antibody
ApplicationELISA, IHC; Recommended dilution: IHC:1:20-1:200