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Acetyl-Histone H2B-K12 Polyclonal Antibody

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Application: IF, IHC, WB
Areas of Research: Histone Methylation (Lysine) Antibodies
Clonality: Acetylated
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Affinity Purified
Reactivity: Human, Mouse, Rat
100% Guarantee: 6 months
Catalog No.SizePriceQty
A72912-05050 µl $289.00 
A72912-100100 µl $439.00 
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Product Overview

Background
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene encodes a replication-dependent histone that is a member of the histone H2B family, and generates two transcripts through the use of the conserved stem-loop termination motif, and the polyA addition motif. The protein has antibacterial and antifungal antimicrobial activity.

Description
Acetyl-Histone H2B-K12 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.

Formulation
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Specificity
Human, Mouse, Rat

Isotype
IgG

Uniprot ID
Q16778

Purification
Affinity Purification

Immunogen
A synthetic acetylated peptide around K12 of human Histone H2B (NP_003519.1).

Storage
Shipped at 4°C. Upon receipt, store at -20°C. Avoid freeze / thaw cycles

Alternative Names
HIST2H2BE; GL105; H2B; H2B.1; H2BFQ; H2BGL105; H2BQ; histone H2B type 2-E

Application
WB, IHC, IF; Recommended dilution: WB 1:500 - 1:2000, IHC 1:50 - 1:200, IF 1:50 - 1:200

User Guide & MSDS

[User Guide]*
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