TXB2 Polyclonal Antibody

Background
Thromboxane B2 (TXB2) is an inactive metabolite/product of thromboxane A2 (TXA2) - an enzyme involved in platelet aggregation, vasoconstriction and reproductive functions, but also known to be highly unstable under physiological conditions due to its very short half-life. TXB2 and its metabolite 2,3-dinor-TXB2 are released in abundant quantities during platelet aggregation and are commonly used to indirectly measure TXA2 production in vivo.  A major metabolite of TXB2, 11-dehydro-TXB2, found in urine and plasma is produced via dehydrogenation by the enzyme 11-OH-dehydrogenase. 

Description
Sheep polyclonal antibody

Formulation
Liquid. Contains sodium azide.

Immunogen
TXB2 conjugated to bovine serum albumin.

Specificity
Species Independent

Purification
Serum

Storage
Store at -20°C. Avoid multiple freeze/thaw cycles.

Alternative Names
Thromboxane B2

Application
ELISA