TPPP Monoclonal Antibody [17C6]

Background
Tubulin polymerization-promoting protein (TPPP) is a brain-specific protein expressed mainly in myelinating oligodendrocytes of the central nervous system. It is thought to play a role in the polymerization of tubulin into microtubules, microtubule bundling and the maintenance of existing microtubules, thereby conserving the integrity of the microtubule network. TPPP may also be involved in mitotic spindle assembly and nuclear envelope breakdown. 

Description
Rat monoclonal antibody to TPPP, Clone 17C6

Formulation
Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.

Immunogen
Full length recombinant TPPP.

Specificity
Human, Mouse, Monkey

Isotype
IgG2a

Purification
Protein G-affinity purified

Storage
Store at +4°C for short term. Aliquot and store at -20°C for long term. Avoid multiple freeze/thaw cycles.

Alternative Names
Tubulin polymerization-promoting protein, p25

Application
ICC (10 µg/ml), IHC (paraffin sections 10 µg/ml), WB (200 ng/ml)