Histone Phosphorylation Antibodies

Antibodies that detect phosphorylated target proteins help researchers to understand the role phosphorylation plays in cellular processes. Phosphorylation can turn numerous protein enzymes on and off by adding a phosphate group to the proteins, thereby affecting their activity and function.

Histone Phosphorylation

Histone phosphorylation is a post-translational modification that occurs on the tail regions of histone proteins. It entails the addition of a phosphate group to specific amino acid residues on the histone tails, which can affect the structure and function of chromatin. The phosphorylation of histones can modulate the accessibility of DNA to the transcriptional machinery, and thus is involved in regulating gene expression. Histone phosphorylation is mediated by specific enzymes called histone kinases, and is reversible, meaning the phosphate group can be removed by histone phosphatases. This dynamic regulation of histone phosphorylation is thought to play an important role in the cell cycle, DNA damage repair, and other processes.

What makes buying antibodies from EpiGentek different?

At EpiGentek, we supply a collection of over 20,000 individual high-quality antibodies for our customers to ensure that our research customers find exactly what they need for their studies. In addition, we offer a variety of other benefits to help our customers in terms of affordability, convenience, and reliability. See why working with EpiGentek for your antibodies is the right choice:

• No Shipping & Handling Costs: we’ve waived all shipping and handling fees on our antibodies and antibody panel packs when selecting 2-day shipping (trial sizes not applicable).
• 100% Application Guarantee: your purchased antibodies are covered for 6-months past the date of purchase.
• Multiple Conjugates: we carry biotin, FITC and HRP conjugates for nearly all targets.
• Trial Sizes Available: 10 & 20 µl options available for thousands of antibodies in our catalog.