Nesfatin-1 Monoclonal Antibody [NESFATY1]

Background
Nesfatin-1 is metabolic polypeptide derived from the posttranslational processing of nucleobindin-2 (NUCB2). Originally recognized as a hypothalamic neuropeptide, it is also found in other parts of the brain, the pancreas, gastric endocrine cells and adipocytes. Involved in the regulation of hunger and fat storage, an increase in the Nasfatin-1 in the hypothalamus has been shown to suppress appetite and promote energy expenditure, independent of leptin signaling.

Description
Mouse monoclonal antibody to Nesfatin-1, Clone NESFATY1

Formulation
Liquid. In PBS containing 0.02% sodium azide

Immunogen
Recombinant rat nesfatin-1 (aa 25-106)

Specificity
Mouse, Rat

Isotype
IgG1

Purification
Protein G- affinity purified

Storage
Store at +4°C for short term. Aliquot and store at -20°C for long term. Avoid multiple freeze/thaw cycles.

Alternative Names
NEFA/nucleobindin2-encoded satiety- and fat-influencing protein, N-terminal fragment of NUCB2, Gastric cancer antigen Zg4

Application
ELISA, IP (1:100), WB (1:1000)