BackgroundMBD3, or methyl-CpG binding domain protein 3, is a protein that is a member of the methyl-CpG-binding domain (MBD) family, which also includes MeCP2, MBD1, MBD2, MBD4, CLLD8-like, and BAZ2A-like proteins. Although MBD3 is a member of the methyl-CpG-binding domain family, it is not able to bind to methylated DNA. It is a subunit of a multisubunit complex known as NuRD, which is involved in nucleosome remodeling and histone deacetylase functions. It is also thought to mediate the relationship of MTA2, or metastasis-associated protein 2, with the histone deacetylase core complex.
DescriptionMBD3 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationBuffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
SpecificityHuman, Mouse
IsotypeIgG
Uniprot IDO95983
PurificationAffinity Purification
ImmunogenRecombinant fusion protein containing a sequence corresponding to amino acids 1-255 of human MBD3 (NP_001268383.1).
StorageShipped at 4°C. Upon receipt, store at -20°C. Avoid freeze / thaw cycles
Alternative NamesAI181826 antibody, AU019209 antibody, MBD 3 antibody, MBD3: methyl CpG binding domain protein 3 antibody, MBD3_HUMAN antibody, Methyl CpG binding protein MBD3 antibody
ApplicationWB; Recommended dilution: WB: 1:200-1:2000