BackgroundDNA methylation is the major modification of eukaryotic genomes and it plays an essential role in mammalian development. Methyl-CpG binding domain protein 1 (MBD1), which can bind to methylated DNA in vivo and in vitro, may serve as a methylation-dependent transcriptional repressor.
DescriptionMBD1 Polyclonal Antibody. Unconjugated. Raised in: Rabbit.
FormulationLiquid. 0.03% Proclin 300, 50% Glycerol, 0.01M PBS, pH 7.4
SpecificityHuman
IsotypeIgG
Uniprot IDQ9UIS9
PurificationProtein G purified
ImmunogenRecombinant Human Methyl-CpG-binding domain protein 1 protein (106-355AA)
StorageUpon receipt, store at -20°C or -80°C. Avoid repeated freeze.
Alternative NamesCXXC 3 antibody, CXXC-type zinc finger protein 3 antibody, MBD 1 antibody, MBD1_HUMAN antibody, MECP1 COMPLEX antibody, Methyl CpG binding domain protein 1 antibody, Methyl CpG binding domain protein 1 isoform PCM1 antibody, Methyl CpG binding protein MBD1 antibody, PCM 1 antibody, Protein containing methyl CpG binding domain 1 antibody, Regulator of fibroblast growth factor 2 (FGF 2) transcription antibody, RFT antibody
ApplicationELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200
VCU0006