Cyclophilin A Polyclonal Antibody

Background
Cyclophilin A, also known as peptidylprolyl isomerase A (PPIA), is gene that encodes a member of the peptidyl-prolyl cis-trans isomerase (PPIase) family. PPIases catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides and accelerate the folding of proteins. The encoded protein is a cyclosporin binding-protein and is thought to play a role in cyclosporin A-mediated immunosuppression. It has also been shown to interact with numerous HIV proteins, including p55 gag, Vpr, and capsid protein, and may be required for the formation of infectious HIV virions. Various pseudogenes that map to different chromosomes have been reported.

Description
Rabbit polyclonal antibody to Cyclophilin A

Formulation
Liquid. Neat serum.

Immunogen
Recombinant human cyclophilin A conjugated to KLH.

Specificity
Human, Mouse, Rat

UniProt ID
P62937

Purification
Serum

Storage
Store at -20°C. Avoid multiple freeze/thaw cycles.

Alternative Names
CyPA, Peptidyl-prolyl cis-trans isomerase A

Application
ICC, WB