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RING1 Polyclonal Antibody

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Application: ChIP, ELISA, IF, IP, WB
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Affinity Purified
Reactivity: Human, Mouse, Rat
Application Guarantee: 6 months
Catalog No.SizePriceQty
A-2021-05050 µg $199.00 
A-2021-100100 µg $369.00 
Availability: Usually Ships In 1-2 Days 
Product Overview

Background 
Polycomb group (PcG) proteins form the multiprotein complexes that are important for the transcriptional repression of various genes involved in development and cell proliferation. RING1 is a PcG protein that contains the RING finger motif, a specific zinc-binding domain that is found in many regulatory proteins. It has been shown that RING1 interacts with transcription factor CP2 (TFCP2/CP2) and suppress the activity of CP2. Also, there is involvement of the gene RING1B in the specification of the anterior-posterior axis as well as in cell proliferation in early development. This protein was also found to interact with huntingtin interacting protein 2 (HIP2), an ubiquitinconjugating enzyme, as well as possess ubiquitin ligase activity.

Concentration
0.2 mg/ml

Description
Rabbit polyclonal antibody to RING1, ChIP-grade

Purification
Protein A purified

Specificity
Mouse, rat, human

Isotype
IgG

Formulation
0.1% Sodium Azide, 0.1% gelatin, PBS

Storage
4°C, stable for 1 year from the date of shipment. Avoid repeated freezing and thawing. Multiple freeze/thaw cycles may result in decreased performance

Alternative Names
Ring1A antibody, E3 ubiquitin-protein ligase RING1 antibody, Polycomb complex protein RING1 antibody, RING finger protein 1 antibody, Rnf1 antibody, Transcription repressor Ring1A antibody

Application
WB: 1:200-1:500, IF: 1:100-1:500, ELISA: 1:1000-1:2000, IP: 2 µg/106 cells

Fig. 1. WB analysis of RING1 Polyclonal Antibody with Ring1 overexpressed cell lysates (A-2021).

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