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PRDM1 Polyclonal Antibody

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WB analysis of PRDM1 Polyclonal Antibody with overexpressed 293T cell lysates (A-2001).
Application: ELISA, IHC
Clonality: Polyclonal
Conjugate: Unconjugated
Host: Rabbit
Isotype: IgG
Purification: Affinity Purified
Reactivity: Human
Guarantee: 6 months
Catalog No.SizePriceQty
A-2001-05050 µg $239.00 
A-2001-100100 µg $409.00 
Availability: Usually Ships In 1-2 Days 
Product Overview

Background
PRDM1 is the human homologue to Blimp-1, a transcriptional repressor affecting multiple key target genes for the terminal differentiation of B-cells along the plasma cell lineage. PRDM1 recruits methyltransferases to their targets, inducing methylation and thus transcriptional repression of those gene targets. Also, the PRDM1 protein binds specifically to the positive regulatory domain I element (PRDI) of the beta-IFN gene promoter. It was also recently demonstrated that PRDM1 plays a tumor suppressor role in diffuse large B- cell lymphomas. 

Description
Rabbit polyclonal antibody to PRDM1

Concentration
0.25 mg/ml

Purification

Protein A purified

Specificity
Positive in human

Isotype
IgG

Formulation
0.1% Sodium Azide, PBS

Storage
4°C, stable for 6 months from the date of shipment. For long-term storage, aliquot and store at -20°C. Avoid repeated freezing and thawing. Multiple freeze/thaw cycles may result in decreased performance

Alternative Names
B Lymphocyte Induced Maturation Protein 1 antibody, Beta interferon gene positive regulatory domain I binding factor antibody, Blimp 1 antibody, MGC118922 antibody, MGC118923 antibody, MGC118924 antibody, MGC118925 antibody, Positive Regulatory Domain I Binding Factor 1 antibody, PR domain containing 1 with ZNF domain isoform 2 antibody, PR domain zinc finger protein 1 antibody, PRDI BF1 antibody, PRDI binding factor 1 antibody

Application
IHC: 1:100-1:500, ELISA: 1:1000-1:2000

Fig. 1. WB analysis of PRDM1 Polyclonal Antibody with overexpressed 293T cell lysates (A-2001).

 

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