HP1-gamma is an isoform of the heterochromatin protein 1 (HP1) which plays a role in chromatin remodeling and transcriptional silencing. The HP1 chromo domain selectively recognizes methylated H3-K9, where this methylation is carried out by histone methyltransferase SUV39H1. SUV39H1-HP1 methylation is important for the correct localization of HP1 at heterochromatin and for transcriptional silencing.
Affinity purified goat polyclonal antibody HP1g (heterochromatin protein 1 gamma, HP1 gamma)
Protein A purified
HP1g, HP1-g, HP1γ, HP1-γ
Mouse, rat, human
0.1% Sodium Azide, 0.1% gelatin, PBS
4ºC, stable for 1 year from the date of shipment. Avoid repeated freezing and thawing. Multiple freeze/thaw cycles may result in decreased performance
CBX 3 antibody, Chromobox homolog 3 (HP1 gamma homolog, Drosophila) antibody, Chromobox protein homolog 3 antibody, GAMMA antibody, HECH antibody, Heterochromatin protein 1 homolog gamma antibody, Heterochromatin protein HP1 gamma antibody, HP1 gamma antibody, HP1Hs gamma antibody, Modifier 2 protein antibody
WB: 1:200-1:500, IF: 1:100-1:500, ELISA: 1:500-1:1000, IP: 2 μg/106 cells
Fig. 1. WB analysis of HP1γ Polyclonal Antibody with K562 cell lysates (A-4017).