Histone deacetylases (HDACs) play a critical role in transcriptional repression of gene expression in eukaryotic cells through catalyzing the hydrolytic removal of acetyl groups from histone lysine residues. Three distinct families of HDACs have been described, comprising a group of at least 20 proteins in humans. HDAC8 is a class I histone deacetylase.
Mouse monoclonal antibody to HDAC8, ChIP-grade.
Mouse, rat, human
0.1% Sodium Azide, 0.1% gelatin, PBS
4ºC, stable for 1 year from the date of shipment. Avoid repeated freezing and thawing. Multiple freeze/thaw cycles may result in decreased performance.
CDA07 antibody, HD 8 antibody, HDACL 1 antibody, Histone deacetylase 8 antibody, Histone deacetylase like 1 antibody, RPD 3 antibody
WB: 1:200-1:500, IF: 1:100-1:200, ELISA: 1:500-1:1000, IP: 2 μg/106 cells
Fig. 1. WB analysis of HDAC8 Monoclonal Antibody with HDA8- overexpressed 293T lysates (A-4008).