Histone deacetylases (HDACs) play a critical role in transcriptional repression of gene expression in eukaryotic cells through catalyzing the hydrolytic removal of acetyl groups from histone lysine residues. Three distinct families of HDACs have been described, comprising a group of at least 20 proteins in humans. HDAC3 is a class I histone deacetylase.
Mouse monoclonal antibody to HDAC3, ChIP-grade
Protein A purified
Mouse, rat, human
0.1% Sodium Azide, 0.1% gelatin, PBS
4ºC, stable for 1 year from the date of shipment. Avoid repeated freezing and thawing. Multiple freeze/thaw cycles may result in decreased performance
HD 3 antibody, histone deacetylase 3 antibody, RPD 3 antibody, RPD3 2 antibody, SMAP 45 antibody, SMAP45 antibody
WB: 1:200-1:500, IF: 1:100-1:200, ELISA: 1:500-1:1000, IP: 2 μg/106 cells
Fig. 1. WB analysis of HDAC3 Monoclonal Antibody with HeLa lysates (A-4003).